Tag: out-of-hospital cardiac arrest (ohca)

Pharmacology News Digest, July 22nd 2018

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4% Decreased Chance of Survival Per Minute Delay in Epinephrine Administration During Cardiac Arrest | Circulation

The majority of patients experiencing out-of-hospital cardiac arrest (OHCA) with nonshockable rhythms in the United States are administered epinephrine more than 10 minutes after cardiac arrest.  A study analyzing data on nonshockable OHCA from the Resuscitation Outcomes Consortium found that early epinephrine administration (<10 minutes after EMS arrival) was associated with significantly higher survival to hospital discharge than late administration.

This data corroborates findings from previous studies demonstrating improved survival of OHCA patients with shockable rhythms receiving early intravenous (adult)/intraosseous(pediatric) epinephrine.  These results underline the importance of rapid prehospital ACLS response in maximizing the chances of OHCA survival.



Source: Time to Epinephrine Administration and Survival From Nonshockable Out-of-Hospital Cardiac Arrest Among Children and Adults | Circulation