Methadone is a synthetic μ-opioid receptor agonist prescribed for the treatment of opioid dependence and withdrawal. It is also used in severe pain conditions at lower doses.
Methadone has a longer half-life and fewer euphoric effects than morphine and other opioids, but still carries a dose-dependent risk of the toxicities associated with this class of drugs. Sedation, dizziness, and headache are common side effects and incorrect dosing or abuse can result in profound sedation, respiratory depression, and death.
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