Cyclosporine, modified (Gengraf®, Neoral®) – Calcineurin Inhibitor

Cyclosporine is a calcineurin inhibitor commonly used as an immunosuppressant following organ transplant.  The drug is typically administered perioperatively during heart, kidney, or lung transplants, and patients often remain on the drug indefinitely following transplantation.

Other uses of the drug include treatment rheumatoid arthritis, severe psoriasis, and the reversal reaction sometimes observed during leprosy infection.

cyclosporine

Citations

  1. Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2017 Nov 8. doi: 10.1093/nar/gkx1037
  2. Epocrates Rx Online [Internet database]. San Mateo (CA): Epocrates, Inc. 2003. Retrieved at mobile.epocrates.com. Web-based; continuous content updates. Accessed 2018 April 20.
  3. “Prescription Prices, Coupons & Pharmacy Information – GoodRx.” Prescription Prices, Coupons & Pharmacy Information – GoodRx, www.goodrx.com
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