Category: Addiction

Bupropion (Wellbutrin®, Forvivo®, Zyban®, Aplenzin®)

Overview

Bupropion is an aminoketone antidepressant medication indicated for the treatment of major depressive disorder and to reduce withdrawal symptoms during smoking cessation. Continue reading “Bupropion (Wellbutrin®, Forvivo®, Zyban®, Aplenzin®)”

Advertisements

Gabapentin (Neurontin®, Gralise®)

Overview

Gabapentin is a neuronal calcium channel blocker and GABA synthesis/degradation modulator used in the treatment of epilepsy involving non-generalizing partial seizures, as well as post-herpetic neuralgia (PHN).  Continue reading “Gabapentin (Neurontin®, Gralise®)”

Methadone (Methadose®, Dolophine®) – Synthetic Opioid

Methadone is a synthetic μ-opioid receptor agonist prescribed for the treatment of opioid dependence and withdrawal.  It is also used in severe pain conditions at lower doses.

Methadone has a longer half-life and fewer euphoric effects than morphine and other opioids, but still carries a dose-dependent risk of the toxicities associated with this class of drugs.  Sedation, dizziness, and headache are common side effects and incorrect dosing or abuse can result in profound sedation, respiratory depression, and death.

methadone

Citations

  1. Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2017 Nov 8. doi: 10.1093/nar/gkx1037
  2. Epocrates Rx Online [Internet database]. San Mateo (CA): Epocrates, Inc. 2003. Retrieved at mobile.epocrates.com. Web-based; continuous content updates. Accessed 2018 April 24.
  3. “Prescription Prices, Coupons & Pharmacy Information – GoodRx.” Prescription Prices, Coupons & Pharmacy Information – GoodRx, www.goodrx.com